ANTI-INFLAMMATORY EFFECT OF BETA-BETA (LUNASIA AMARA ) IN WISTAR RATS

Hasnaeni, Hasnaeni ANTI-INFLAMMATORY EFFECT OF BETA-BETA (LUNASIA AMARA ) IN WISTAR RATS. In: 1ST International conference on Heath Science, Oktober 2016.

Text (URL SEMINAR NASIONAL) 336552412_ANTIINFLAMMATORY_EFFECT_OF_BETA-BETA_Lunasia_amara_in_WISTAR_RATS_KESIMPULAN_Bayam_duri_Ammaranthus_sp Download (298kB)

Abstract

Introduction. The Beta-beta (Lunasia amara) extract is being used orally and topically in traditionalIndonesia for the treatment of leg swelling, skin diseases and inflammation or irritation of the eyes. Theanti-inflammatory effect of beta-beta wood were tested in rats induced Complete Freund’s Adjuvant(CFA) 0,1%.Aim. Test the effect anti-inflammatory of beta-beta wood (Lunasia amara) in Wistar rats.Methods. Anti-inflammatory effects of beta-beta was observed at the foot of Wistar rats inducedComplete Freund's Adjuvant (CFA). Animals were divided into 6 groups with each group consisting of 6animals: the group given extract beta-beta at a dose of 5 mg/kg body weight (BW) and 10 mg/kg BW,group given a fraction of beta-beta and a control group that controls positive, normal controls andnegative controls. Antiinflammatory effect was observed through a decrease in volume of edema in ratsinduced foot CFA. Edema volume measurements using a pletismometer.Results. Beta-beta wood has anti-inflamamtory effect in Wistar rats induced CFA. The measurementresults between the group given the extract and the fraction of the beta-beta wood compared withdiclofenac sodium control group showed no significant difference (p˂0,05).Conclusion. Beta-beta wood (Lunasia amara) has anti-inflammatory effects in Wistar rats.Keyword : Anti-inflammatory, beta-beta (Lunasia amara), Wistar rats, Complete Freund’s adjuvant(CFA), pletismometer

Item Type:	Conference or Workshop Item (Paper)
Subjects:	R Medicine > RS Pharmacy and materia medica
Divisions:	FAKULTAS FARMASI
Depositing User:	Unnamed user with email admin@umi.ac.id
Date Deposited:	16 Feb 2021 02:43
Last Modified:	16 Feb 2021 02:43
URI:	http://repository.umi.ac.id/id/eprint/218

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