AKTIVITAS ANTIBAKTERI EKSTRAK ETANOL KULIT BUAH PINANG (Areca catechu L) TERHADAP PERTUMBUHAN BAKTERI UJI Streptococcus mutans DAN Porphyromonas gingivalis

Rahmayanti, Hani and Nuryanti, Siska and Herwin, Herwin (2024) AKTIVITAS ANTIBAKTERI EKSTRAK ETANOL KULIT BUAH PINANG (Areca catechu L) TERHADAP PERTUMBUHAN BAKTERI UJI Streptococcus mutans DAN Porphyromonas gingivalis. Other thesis, Universitas Muslim Indonesia.

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Abstract

HANI RAHMAYANTI. Aktivitas Antibakteri Ekstrak Etanol Kulit Buah Piang (Areca catechu L.) Terhadap Pertumbuhan Bakteri Uji Streptococcus mutans dan Porphyromonas gingivalis (Dibimbing oleh Siska Nuryanti dan Herwin). Kulit buah pinang (Areca catechu L.) merupakan tanaman yang memiliki banyak kegunaan serta dapat dimanfaatkan untuk pengobatan tradisional. Kulit buah pinang dapat digunakan untuk mengatasi gangguan pencernaan (dispepsia), edema dan beri-beri karena urine yang sedikit. Penelitian ini bertujuan untuk menentukan aktivitas antibakteri ekstrak etanol kulit buah pinang terhadap bakteri uji Streptococcus mutans dan Porphyromonas gingivalis. Pada penelitian ini, simplisia kulit buah pinang dilakukan proses ekstraksi menggunakan metode maserasi dengan pelarut etanol 96%, setelah itu diperoleh ekstrak etanol cair kemudian diuapkan dengan menggunakan Rotary vakum evaporator sehingga diperoleh ekstrak kental. Setelah didapatkan ekstrak kental dilakukan uji Minimum Inhibitor Concentration (MIC) dan Uji Minimum Bactericidal Concentration (MBC). Hasil yang diperoleh pada uji Minimum Inhibitor Concentration (MIC) dan uji Minimum Bactericidal Concentration (MBC) pada bakteri Streptococcus mutans dan Porphyromonas gingivalis yaitu 0,5%. uji aktivitas antibakteri dengan metode difusi agar diperoleh, untuk bakteri Streptococcus mutans diameter zona hambat terbesar pada konsentrasi 16% yaitu 12,58 mm dan bakteri Porphyromonas gingivalis pada konsentrasi 16% yaitu 10,93 mm. Berdasarkan penelitian, ekstrak etanol kulit buah pinang memiliki potensi sebagai antibakteri. Kata kunci : Antibakteri, Areca catechu, Streptococcus mutanas, Porphyromonas gingivalis ABSTRACT HANI RAHMAYANTI. Antibacterial Activity of Ethanol Extract of Piang Fruit Peel (Areca catechu L.) Against the Growth of Test Bacteria Streptococcus mutans and Porphyromonas gingivalis (Supervised by Siska Nuryanti and Herwin). Areca nut (Areca catechu L.) is a plant that has many uses and can be used for traditional medicine. Areca nut skin can be used to treat indigestion (dyspepsia), edema and beriberi due to low urine output. This study aims to determine the antibacterial activity of ethanol extract of areca nut peel against the test bacteria Streptococcus mutans and Porphyromonas gingivalis. In this research, the areca nut peel simplicia was extracted using the maceration method with 96% ethanol solvent, after which a liquid ethanol extract was obtained and then evaporated using a rotary vacuum evaporator to obtain a thick extract. After the extract is thick, a Minimum Inhibitor Concentration (MIC) test and a Minimum Bactericide Concentration (MBC) test are carried out. The results obtained in the Minimum Inhibitor Concentration (MIC) test and Minimum Bactericide Concentration (MBC) test on Streptococcus mutans and Porphyromonas gingivalis bacteria were 0.5%. Antibacterial activity test using the agar diffusion method was obtained, for Streptococcus mutans bacteria, the largest inhibitory zone diameter at a concentration of 16% was 12.58 mm and for Porphyromonas gingivalis bacteria at a concentration of 16%, namely 10.93 mm. Based on research, ethanol extract of areca nut peel has antibacterial potential. Keywords: Antibacterial, Areca catechu, Streptococcus mutanas, Porphyromonas gingivalis

Item Type: Thesis (Other)
Subjects: R Medicine > RS Pharmacy and materia medica
Divisions: FAKULTAS FARMASI
Depositing User: operator 10
Date Deposited: 27 May 2024 02:09
Last Modified: 27 May 2024 02:09
URI: http://repository.umi.ac.id/id/eprint/6404

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