EVALUATION OF THE FREE RADICAL SCAVENGING OF TECTOQUINONE COMPOUND ISOLATED FROM SYZYGIUM OBLANCEOLATUM (C.B.ROB.) MERR

Najib, Ahmad and Handayani, Virsa and Jaelani, Muhammad Rizki (2023) EVALUATION OF THE FREE RADICAL SCAVENGING OF TECTOQUINONE COMPOUND ISOLATED FROM SYZYGIUM OBLANCEOLATUM (C.B.ROB.) MERR. Universal Journal of Pharmaceutical Research, 8. pp. 10-14. ISSN 2831-5235

Text EVALUATION OF THE FREE RADICAL SCAVENGING OF TECTOQUINONE (2).pdf Download (997kB)

Abstract

Aim and objective: In this study, the free radical scavenging of tectoquinone compound isolated from leaf of Syzygium oblanceolatum (C.B. Rob.) Merr was investigated by assessing their capacity to scavenge free radicals using the DPPH (2, 2-diphenyl-1-picrylhydrazyl) assay. Methods: The quantitative assessment of antioxidant activity was conducted using a UV-Vis spectrophotometric approach, with measurements taken at a wavelength of 516 nm. Results: The IC50 value, representing the concentration required to inhibit 50% of the DPPH radicals, was determined to be 66.362 μg/mL, indicating a moderate free radical-scavenging activity. Conclusion: These findings suggest that tectoquinone compounds possess a discernible ability to against free radical, though further research may be necessary to optimize their potential applications in health and medicine. Keywords: DPPH assay, free radical, IC50 value, Syzygium oblanceolatum, Tectoquinone.

Item Type:	Article
Subjects:	R Medicine > RS Pharmacy and materia medica
Divisions:	FAKULTAS FARMASI
Depositing User:	operator 10
Date Deposited:	02 Jul 2024 03:18
Last Modified:	02 Jul 2024 03:18
URI:	http://repository.umi.ac.id/id/eprint/6512

Actions (login required)

View Item