Hakim, Azalia Azizah Wardhani and Herwin, Herwin and Fitriana, Fitriana (2024) UJI AKTIVITAS EKSTRAK ETANOL DAUN MATOA (Pometia pinnata J.R & G.Fors) TERHADAP BAKTERI PENYEBAB INFEKSI SALURAN PENCERNAAN. Other thesis, Universitas Muslim Indonesia.
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Abstract
AZALIA AZIZAH WARDHANI HAKIM, Antibacterial Activity of Ethanol Extract of Matoa Leaves (Pometia Pinnata J.R & G.Fors.) against Bacteria Causing Gastrointestinal Infections (Supervised by Herwin and Fitriana) Matoa leaves (Pometia pinnata J.R & G.Fors.) empirically can treat various diseases such as hypertension, diarrhea, dysentery and contain flavonoids, tannins and saponins which function as antibacterials. This study aimed to examine the antibacterial assay of the ethanol extract of Pometia pinnata J.R & G.Fors leaves on bacteria causing gastrointestinal infections using agar diffusion. Then, it continued on antibacterial screening using concentrations of 0.1% and 0.5%, Minimum Inhibitory Concentration testing (MIC), and Minimum Bactericidal Concentration (MBC) testing using different concentrations of 0.0125%, 0.025%, 0.05%, 0.1%, 0.2%, 0.4%, 0.8%, 1.6% on E. coli, V. cholerae and S. dysenteriae bacteria. The results from the screening test at 0.1% concentration showed activity against E. coli and S. dysentriae while V. cholerae and S. typhi did not indicate any reaction. Further, a concentration of 0.5% reported activity against E. coli, S. dysentriae and V. cholerae bacteria, but S. typhi bacteria did not prove reaction. The MIC test results obtained values at 0.0125% in E. coli, V. cholerae, and S. Dysentriae and MBC value at the concentration found 0.2% in E. coli, V. cholerae and S. dysentriae. Meanwhile, the results of the antibacterial assay of the ethanol extract of Matoa leaves confirmed the largest diameter of the inhibition zone at a concentration of 1.6% and 11.36 mm in V. cholerae bacteria. Based on these results, it can be concluded that the ethanol extract of matoa leaves contains antibacterial activity against bacteria causing gastrointestinal infections such as E. coli, V. cholerae, and S. dysentriae. Keywords : Antibacterial, Matoa Leaves (Pometia pinnata J.R & G.Fors.), and Gastrointestinal infection
| Item Type: | Thesis (Other) |
|---|---|
| Subjects: | R Medicine > R Medicine (General) R Medicine > RS Pharmacy and materia medica |
| Divisions: | FAKULTAS FARMASI |
| Depositing User: | operator 10 |
| Date Deposited: | 10 Oct 2024 03:26 |
| Last Modified: | 10 Oct 2024 03:26 |
| URI: | http://repository.umi.ac.id/id/eprint/7009 |
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