FORMULASI SEDIAAN TABLET HISAP EKSTRAK DAUN MIANA (Coleus scutellarioides L)

Haris, Zulfiah and Mirawati, Mirawati and Nurlina, Nurlina (2023) FORMULASI SEDIAAN TABLET HISAP EKSTRAK DAUN MIANA (Coleus scutellarioides L). Other thesis, Universitas Muslim Indonesia.

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Abstract

ZULFIAH HARIS. Formulasi Sediaan Tablet Hisap Ekstrak Daun Miana (Coleus scutellarioides L). Daun miana (Coleus scutellarioides L) secara empiris digunakan sebagai obat untuk batuk. Penelitian ini bertujuan untuk mengembangkan menjadi sebuah formula tablet hisap yang stabil secara farmasetik. Ekstraksi daun miana dilakukan dengan maserasi menggunakan pelarut etanol 96%. Ekstrak daun miana digunakan sebagai zat aktif pada formulasi dengan tiga jenis formula tablet. Variasi pengikat formula I,II dan III berturut-turut (PVP 4%), (PVP 2% dan Gom arab 2%), dan (Gom arab 4%). Hasil evaluasi granul dan evaluasi tablet didapatkan bahwa semua formula memiliki karakteristik yang baik secara farmasetik berdasarkan parameter evaluasi yang telah dilakukan. Kata kunci : Ekstrak daun miana, PVP- K30, Gom arab, Tablet hisap ABSTRACT ZULFIAH HARIS. Lozenge Formulation from Painted Nettle (Coleus scutellarioides L) Leaf Extracts Empirically, painted nettle leaves (Coleus scutellarioides L) have been utilised to treat cough. This research aimed to develop painted nettle leaves into a pharmacologically stable lozenge formula. To start with, the study conducted the leaf extraction by maceration using 96% ethanol. Next, the extract was applied as an active substance in formulations with three types of tablet formulas. The binder variations for Formula I, II, and III were (PVP 4%), (PVP 2% and Gum arabic 2%), and (Gum arabic 4%), respectively. The results of granule evaluation and tablet evaluation found that all formulas have pharmacologically indicated good characteristics based on the evaluation parameters carried out. Keywords: Painted nettle leaf extract, PVP-K30, Gum Arabic, Lozenges

Item Type:	Thesis (Other)
Subjects:	Q Science > Q Science (General) R Medicine > R Medicine (General) R Medicine > RS Pharmacy and materia medica
Divisions:	FAKULTAS FARMASI
Depositing User:	operator 10
Date Deposited:	10 Oct 2024 03:28
Last Modified:	10 Oct 2024 03:28
URI:	http://repository.umi.ac.id/id/eprint/7037

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