EFFECT INFLAMMATORY OF LUNASIA AMARA EXTRACT ETHANOLIC ON EXPERIMENTAL CHRONIC ARTHRITIS

The effect inflammatory of Lunasia amara ethanol
extract (LAE) on Freund’s complete adjuvant
(FCA)-induced arthritis were investigated. Effect
inflammatory assessment was done by measuring –
paw volume (hind paw swelling), joint diameter and
body weight. The oral administration of LAE (50,
100 and 200 mg/kg BW per day) for 60 days after
subcutaneous immunization with FCA. The arthritis
score and paw edema were markedly suppressed in
the groups treated with LAE. The result suggest that
the Lunasia amara Extract ethanolic might be
beneficial in the treatment of chronic inflammatory
disorder.
Keyword : Lunasia amara extract ethanolic, chronic
inflammation, FCA-induced arthritis