Passiflora foetida Linn activity against streptozotocin-induced diabetic mice from South Sulawesi, Indonesia

This study aimed to examine the effect of Passiflora foetida Linnextractsat a dose of 400 mg/kgbw against streptozotocin-induced diabetic mice. This research used 30 male mice which divided into three treatment groups. The groups arethe control group,the Streptocotozin (SZT) group, and the group of ethanol extract of thePassiflora foetida Linn herb for dose of 400 mg/kgbw. All groups were induced by SZT except control group.Blood glucose levels were measured before and after mice induced intraperitoneally with STZ dose 100 mg/kgbw. Statistical analysis showed that the control group and STZ group were significantly different (p<0.05). The SZT group showed significantly different (p<0.05) fromextract doseof 400 mg/kgbw in mice. Based on the results, this study concluded that the ethanol extract of Passiflora foetida Linn has effect on lowering blood glucose levels in diabetic mice.