The Effect of Trigona Honey as a Therapy for Burns in Rattus Norvegicus

Introduction: Wound healing is an important physiological process to maintain skin integrity after trauma.
Contact burns are damage or loss of tissue caused by heat sources. The growing interest in natural therapies
has prompted the exploration of trigona honey due to its antioxidant, anti-inflammatory, and antimicrobial
properties. Another study discusses trigona honey on an incised wound, but only a few discuss burns. This
study evaluates the effectiveness of Trigona spp honey as a therapy for burns in Rattus norvegicus.
Methods: A quasi-experimental with a non-randomized control group pretest-posttest design method. In this
study used 20 subjects, there are Rattus norvegicus of the Sprague Dawley strain weighing 100-250 grams
and aged 2-3 months, divided into 5 subjects for 4 groups. This study assesses wound size and use one-way
ANOVA as the analysis technique.
Result: There is significant wound healing initially in all groups before intervention, average wound area
is 3.5 cm. Then treatment was given for 15 days and it was seen that the group with the best wound healing
was treatment on group II (Trigona honey 2 g) with an average wound area of 0.42 cm, followed by
treatment group I (Trigona honey 1 g) is 0.72 cm, followed by the positive control group (silver sulfadizine
0.5 g) is 0.86 cm and then on negative control group (aquadest) is 1.74 cm. In the one-way ANOVA test,
the P value (Between Groups) was 0.000 (<5%).
Conclusion: Trigona honey is effective as a therapy for burns in rattus norvegicus