Pratiwi, Dita and Fitriana, Fitriana and Amirah, Sitti (2023) UJI AKTIVITAS ANTIBAKTERI EKSTRAK ETANOL DAUN BENALU BATU (Begonia medicinalis) TERHADAP BAKTERI UJI PENYEBAB INFEKSI SALURAN PENCERNAAN. Other thesis, Universitas Muslim Indonesia.
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Lembar Pengesahan - DITA PRATIWI.pdf Download (266kB) |
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DAFTAR ISI - DITA PRATIWI.pdf Download (157kB) |
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abstrak - DITA PRATIWI.pdf Download (631kB) |
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BAB 1 - DITA PRATIWI.pdf Download (602kB) |
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DAFTAR PUSTAKA - DITA PRATIWI.pdf Download (362kB) |
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Abstract
DITA PRATIWI, Aktivitas antibakteri ekstrak etanol daun benalu batu (Begonia medicinalis) terhadap bakteri uji penyebab infeksi saluran pencernaan (Dibimbing Oleh Fitriana dan Sitti Amirah). Benalu batu (Begonia medicinalis) mengandung senyawa sekunder seperti polifenol, saponin, flavonoid, dan tannin yang mempunyai aktivitas sebagai antimikroba. Penelitian ini bertujuan untuk mengetahui aktivitas antimikroba dari ekstrak etanol daun benalu batu terhadap bakteri penyebab infeksi saluran pencernaan. Hasil penelitian yang diperoleh pada uji skrining terhadap bakteri uji Escherichia coli, Salmonella typhi, Shigella dysenteriae, dan Vibrio chloreae memberikan aktivitas pada konsentrasi 6% untuk bakteri E. Coli, S. Dysenteriae V. Cholerae. Pengujian dilanjutkan dengan penentuan nilai KHM menggunakan metode dilusi cair dan KBM menggunakan metode dilusi padat. Hasil uji KHM yang diperoleh pada konsentrasi 1% terhadap bakteri uji. Hasil uji KBM yang diperoleh yaitu 18% untuk bakteri E. Coli, 12% untuk bakteri S.Dysenteriae, dan 6% untuk bakteri V. Cholerae. Selanjutnya dilakukan pengujian aktivitas antimikroba menggunakan metode difusi agar dengan seri konsentrasi yaitu 18%, 24%, dan 30%. Hasil uji aktivitas antibakteri ekstrak etanol daun benalu batu diperoleh diameter zona hambatan terbesar pada konsentrasi 30%. Hasil uji statistik data diameter zona hambatan menunjukkan adanya perbedaan kemampuan penghambatan pertumbuhan bakteri antara konsentrasi 18% dan 24% serta 18% dan 30%, kemudian antara konsentrasi 24% dan 30% memiliki kemampuan yang sama dalam menghambat pertumbuhan bakteri. Berdasarkan penelitian, ekstrak etanol daun benalu batu memiliki potensi sebagai antibakteri. Kata kunci: Antimikroba, Daun benalu batu, Difusi agar, dan Infeksi saluran pencernaan DITA PRATIWI, Antibacterial activity of ethanol extract of stone parasite (Begonia medicinalis) against test bacteria that cause digestive tract infections (Supervised by Fitriana and Sitti Amirah). Parasite stone (Begonia medicinalis) contains secondary compounds such as polyphenols, saponins, flavonoids, and tannins which have antimicrobial activity. This study aims to determine the antimicrobial activity of the ethanol extract of parasite leaves against bacteria that cause digestive tract infections. The results obtained in the screening test for Escherichia coli, Salmonella typhi, Shigella dysenteriae, and Vibrio chloreae showed activity at a concentration of 6% for E. Coli, S. dysentriae V. Cholerae bacteria. The test continued with determining the MIC value using the liquid dilution method and the KBM using the solid dilution. method. MIC test results obtained at a concentration of 1% against the test bacteria. The KBM test results obtained were 18% for E. Coli bacteria, 12% for S. Dysentriae bacteria, and 6% for V. Cholerae bacteria. Then tested the antimicrobial activity using the agar diffusion method with a concentration series of 18%, 24%, and 30%. The results of the antibacterial activity test of the ethanol extract of stone parasite leaves obtained the largest diameter of the inhibition zone at a concentration of 30%. The results of statistical test data on the diameter of the inhibition zone showed that there was a difference in the ability to inhibit bacterial growth between concentrations of 18% and 24% and 18% and 30%, then between concentrations of 24% and 30% had the same ability to inhibit bacterial growth. Based on research, the ethanol extract of stone parasite leaves has potential as an antibacterial. Keywords: Antibacterial, Stone parasite leaves (Begonia medicinalis), and digestive tract infections
| Item Type: | Thesis (Other) |
|---|---|
| Subjects: | L Education > L Education (General) Q Science > Q Science (General) R Medicine > R Medicine (General) R Medicine > RS Pharmacy and materia medica |
| Divisions: | FAKULTAS FARMASI |
| Depositing User: | operator 10 |
| Date Deposited: | 10 Oct 2024 03:28 |
| Last Modified: | 10 Oct 2024 03:28 |
| URI: | http://repository.umi.ac.id/id/eprint/7019 |
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